| DISCLAIMER
The purpose of this article is to educate. This article does not constitute medical advice, diagnosis or treatment and is not a substitute for examination, testing, diagnosis and treatment, by a qualified, licensed health care professional.
Frequently, Florida Detox and Wellness Institute can prescribe non-opiate transdermal pain creams to control any pain persisting after detox. Transdermal delivery bypasses the digestive system and first pass liver metabolism, reducing medication interactions and side effects. Powerful pain killers including ketamine or ketaprofen, can be delivered through the skin without side effects, which would occur if they were ingested. Research verifies the safety of transdermal pain killer application.
Only about 1% of the transdermal NSAID is absorbed systemically. Researchers obtained blood samples from the participants to measure system absorption of ketoprofen. They found that serum ketoprofen levels at 24 and 48 hours were minimal.
Non-Steroidal Anti-Inflammatory Drug Applied to Skin Lessens Muscle Soreness After Exercise (news release, San Diego: University of California, San Diego, July 11, 2003) health.ucsd.edu/news/2003/07_11_Bracker.html (accessed 28 July 2003).
The following article reports “The systemic concentrations of ketoprofen have also been found to be 100 fold lower compared to tissue concentrations below the application site in patients undergoing knee joint surgery. Topically applied ketoprofen thus provides high local concentration below the site of application but lower systemic exposure.”
Pharm Res. 1996 Jan;13(1):168-72
Published research indicates Clonidine reduced oralfacial neuralgia pain, an average of 94 %, with complete pain reduction in half of patients.
Epstein J, Grushka M, Le N. Topical clonidine for orofacial pain: a pilot study. J Orofac Pain. 1997 Fall;11(4):346-52. Related Articles, Links
Compounding pharmacists can formulate these creams to penetrate to needed tissue depth, whether it is epidermal, intramuscular or spinal. Muscle relaxants, including Flexeril, Soma, and Skelaxin;anticonvulsants(Tegretol, Gabapentin), antidepressants(Amitriptyline), alpha adrenergic agonists (Clonidine), GABA B agonists(Baclofen), lidocaine, ketamine, ketoprofen, dexmethorphan, amantadine and other medications can be formulated into these transdermal creams to block various types of pain, without risk of addiction, dependency or gastritis. Lidocaine can often be used, when patients are allergic to other medications, although it only has a 2 hour half life. Flexeril has a half life of 8 to 18 hours and can provide longer lasting pain relief. Elavil has an even longer half life of 24 hours and seems especially helpful for arthritis pain. Transdermal pain creams can numb pain, without numbing the brain. Prescription pain creams are effective for back, joint and muscle pain and work well for arthritis and fibromyalgia. Prescription pain creams can also eliminate “pins and needles” nerve pain. Transdermal pain formulas help patients previously disabled by pain return to work, college or caring for their families.
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Steven Sponaugle
Research Director, Florida Detox
www.floridadetox.com |
